Five ways to start. One care team.

Semaglutide

The most-prescribed starting point. Semaglutide is a GLP-1 receptor agonist that helps regulate appetite and slow stomach emptying, so you feel full sooner and stay satisfied longer. In the STEP 1 clinical trial of semaglutide 2.4 mg, adults lost an average of ~15% of body weight over 68 weeks alongside diet and exercise.¹

• Dosing Weekly subcutaneous injection; started low and titrated up over several months
• Best for First-time GLP-1 patients; predictable flat pricing
• Common side effects Nausea, constipation, diarrhea, reduced appetite — usually strongest during dose increases
• Not for you if Personal/family history of medullary thyroid carcinoma or MEN 2, history of pancreatitis, pregnancy

Tirzepatide

A dual-action option: tirzepatide activates both GIP and GLP-1 receptors. In the SURMOUNT-1 trial of tirzepatide, adults lost up to ~21% of body weight on the highest dose over 72 weeks alongside diet and exercise.² Often chosen by patients who plateaued on semaglutide or want the strongest studied effect.

• Dosing Weekly subcutaneous injection; titrated up gradually
• Best for Patients seeking maximum studied weight loss; semaglutide plateaus
• Common side effects Similar GI profile to semaglutide; often reported as milder nausea
• Not for you if Same exclusions as semaglutide (MTC/MEN 2, pancreatitis history, pregnancy)

Oral Dissolving Tablets

Semaglutide in a daily sublingual tablet that dissolves under the tongue — no needles, no refrigeration, easy to travel with. A good fit if injections are a dealbreaker. Oral absorption differs from injections, and your provider will discuss realistic expectations.

• Dosing One tablet dissolved under the tongue daily
• Best for Needle-averse patients; frequent travelers
• Common side effects Same GI class effects; typically milder at oral doses
• Not for you if Same exclusions as injectable GLP-1s

Wegovy® and Zepbound®

Prefer the FDA-approved brand products? Our providers can prescribe Wegovy® (semaglutide) or Zepbound® (tirzepatide) to be filled at a retail or manufacturer pharmacy. Your membership covers the provider relationship, check-ins, and care-team support; you pay the pharmacy directly for medication, where insurance or manufacturer savings programs may reduce your cost substantially.

• Dosing Weekly pen injection (both); Wegovy® also available as a daily pill
• Best for Patients with insurance coverage or who want FDA-approved products
• Cost note Without insurance, brand list prices commonly run $350–$1,350/mo depending on program and dose
• Availability Subject to change with manufacturer supply